Top-10 Biopharma Case Study: $100M+ in R&D Spend Orchestrated

A Decade of Partnership Driving Scale, Savings & Speed in Global R&D

EXECUTIVE SUMMARY

Eleven Years of Partnership, $100M+ in Orchestrated R&D Spend, and a New Model for Active Cost Discipline

A top-10 global biopharmaceutical company — headquartered in the United Kingdom, with R&D operations across 30+ sites in four continents — has partnered with Science Exchange since 2015. Over more than a decade, the relationship has evolved from a single procurement pilot into the foundational infrastructure through which the company sources, contracts, and manages external R&D across its global footprint.

What began as an investment in procurement efficiency has matured into a strategic operating capability. In 2025, the partnership extended further with a joint Savings Initiative — repositioning Science Exchange not only as the infrastructure layer for external R&D, but as an active partner in delivering measurable cost discipline.

$100M+ in R&D spend orchestrated through the platform since 2015
295 unique suppliers actively engaged under one master agreement
~6× order volume growth from 2022 to 2025 (86 → 505 completed orders)
445 active researchers and procurement users across global sites

In its first year, the Savings Initiative delivered a 10% supplier discount the company had previously been unable to secure through years of direct negotiation — early evidence of the platform’s shift from passive transaction layer to active procurement partner.

The Challenge

Scaling External R&D Without Losing Control of Cost and Complexity

The company’s R&D investment has grown approximately 90% since 2016, with a pipeline now spanning more than 60 assets in clinical development. But the mechanisms used to engage external science were not built to scale at the same pace. Across a distributed global footprint, supplier engagement and negotiation remained decentralized — limiting enterprise-wide visibility into who was being engaged, on what terms, and at what aggregate cost.

Global Scale, Distributed Ownership

R&D operations across 30+ sites in the UK, US, EU, India, Asia-Pacific, and Canada meant supplier relationships and engagement standards lived in many places at once — with no single source of truth for activity, terms, or total cost.

Rising External Spend

External research spend expanded alongside pipeline growth. Without a centralized layer, procurement had limited visibility into supplier concentration, duplicated engagements, and pricing inconsistencies across regions.

Untapped Enterprise Leverage

When research teams negotiate independently, the company cannot fully apply the purchasing power of the broader enterprise. Discounts achievable at global scale often remained inaccessible at the engagement level.

From Reactive to Proactive

Procurement leadership sought to evolve from a reactive cost-tracking function into a proactive cost-discipline partner — one that could quantify value and influence sourcing decisions, not just report on them.

The Solution

From Infrastructure to Strategic Procurement Partnership

Phase One (2015–2024): Establishing the Infrastructure Layer

Over the first decade of partnership, Science Exchange became the unified front door for external R&D sourcing across the company’s global footprint. Researchers across sites used the same platform to scope, contract, manage, and pay for external scientific services — replacing fragmented, site-specific workflows with a standardized experience supported by unified compliance, contracting, and payment infrastructure.

Phase Two (2025–Present): Activating Cost Discipline at Scale

In 2025, the partnership entered a new phase with the launch of a dedicated Savings Initiative. Through this joint program, a Science Exchange-led team takes an active role in supplier-level cost negotiation on behalf of the company’s research teams — identifying pricing opportunities, pursuing discounts, and tracking realized savings against defined annual targets, with shared performance commitments.

The Results

Compounding Adoption, Expanding Scale, and Early Proof of Savings

The trajectory of the partnership reflects a compounding model of value creation. More teams, sites, and use cases have converged onto a single platform — transforming Science Exchange from an optional tool into the default mechanism for engaging external R&D across the organization.

A growth curve, not a single moment
Completed orders processed through Science Exchange, year by year:

2022
86 completed orders
2023
172 completed orders
2024
296 completed orders
2025
505 completed orders

Annual external R&D spend grew in parallel — from approximately $5.5M in 2022 to nearly $19M in 2025, with cumulative spend now exceeding $100M.

Scale at a glance

Early proof of active savings The Savings Initiative is still in its first year, but it has already produced a meaningful proof point: a 10% supplier discount negotiated by the Science Exchange team — on a supplier the company had been unable to secure a discount with through years of direct negotiation. The outcome is now serving as a template for similar engagements with other enterprise customers.

A Lasting Partnership

Why This Model Sustains and Scales Over Time

The durability of this partnership reflects four design principles that align with how global R&D organizations actually operate.

The Operating Layer Behind Modern R&D Execution

For this top-10 global biopharmaceutical company, Science Exchange has become more than a procurement platform. Over more than a decade, it has evolved into the operating layer through which external R&D is executed — connecting researchers, suppliers, and procurement in a single system that supports both scale and control.

The introduction of active savings marks the next phase. As R&D investment continues to rise, organizations are no longer looking solely for visibility into external spend — they are looking for mechanisms that directly shape outcomes.