# A Decade of Partnership Driving Scale, Savings & Speed in Global R&D

### EXECUTIVE SUMMARY

Eleven Years of Partnership, $100M+ in Orchestrated R&D Spend, and a New Model for Active Cost Discipline

A top-10 global biopharmaceutical company — headquartered in the United Kingdom, with R&D operations across 30+ sites in four continents — has partnered with Science Exchange since 2015. Over more than a decade, the relationship has evolved from a single procurement pilot into the foundational infrastructure through which the company sources, contracts, and manages external R&D across its global footprint.

What began as an investment in procurement efficiency has matured into a strategic operating capability. In 2025, the partnership extended further with a joint Savings Initiative — repositioning Science Exchange not only as the infrastructure layer for external R&D, but as an active partner in delivering measurable cost discipline.

$100M+
in R&D spend orchestrated through the platform since 2015  
295
unique suppliers actively engaged under one master agreement  
~6×
order volume growth from 2022 to 2025 (86 → 505 completed orders)  
445
active researchers and procurement users across global sites

In its first year, the Savings Initiative delivered a 10% supplier discount the company had previously been unable to secure through years of direct negotiation — early evidence of the platform’s shift from passive transaction layer to active procurement partner.

## The Challenge

### Scaling External R&D Without Losing Control of Cost and Complexity

The company’s R&D investment has grown approximately 90% since 2016, with a pipeline now spanning more than 60 assets in clinical development. But the mechanisms used to engage external science were not built to scale at the same pace. Across a distributed global footprint, supplier engagement and negotiation remained decentralized — limiting enterprise-wide visibility into who was being engaged, on what terms, and at what aggregate cost.

**Global Scale, Distributed Ownership**

R&D operations across 30+ sites in the UK, US, EU, India, Asia-Pacific, and Canada meant supplier relationships and engagement standards lived in many places at once — with no single source of truth for activity, terms, or total cost.

**Rising External Spend**

External research spend expanded alongside pipeline growth. Without a centralized layer, procurement had limited visibility into supplier concentration, duplicated engagements, and pricing inconsistencies across regions.

**Untapped Enterprise Leverage**

When research teams negotiate independently, the company cannot fully apply the purchasing power of the broader enterprise. Discounts achievable at global scale often remained inaccessible at the engagement level.

**From Reactive to Proactive**

Procurement leadership sought to evolve from a reactive cost-tracking function into a proactive cost-discipline partner — one that could quantify value and influence sourcing decisions, not just report on them.

## The Solution

### From Infrastructure to Strategic Procurement Partnership

**Phase One (2015–2024):** Establishing the Infrastructure Layer

Over the first decade of partnership, Science Exchange became the unified front door for external R&D sourcing across the company’s global footprint. Researchers across sites used the same platform to scope, contract, manage, and pay for external scientific services — replacing fragmented, site-specific workflows with a standardized experience supported by unified compliance, contracting, and payment infrastructure.

**Phase Two (2025–Present):** Activating Cost Discipline at Scale

In 2025, the partnership entered a new phase with the launch of a dedicated Savings Initiative. Through this joint program, a Science Exchange-led team takes an active role in supplier-level cost negotiation on behalf of the company’s research teams — identifying pricing opportunities, pursuing discounts, and tracking realized savings against defined annual targets, with shared performance commitments.

- One global platform for external R&D
  A single interface used by 445 researchers and procurement users across 30+ sites — for sourcing, contracting, milestone tracking, and payment.

- Curated supplier network under one agreement
  295 actively engaged suppliers operate under a single master agreement, giving researchers fast access to specialized capability while reducing per-engagement contracting burden.

- Active supplier negotiation as a service
  A dedicated team identifies supplier-level savings opportunities, negotiates on the company’s behalf, and tracks realized savings against defined annual targets.

- Native integration with enterprise systems
  Science Exchange integrates with the company’s procurement, content management, and analytics infrastructure — including SharePoint, ELN, Ariba, and Power BI.

## The Results

### Compounding Adoption, Expanding Scale, and Early Proof of Savings

The trajectory of the partnership reflects a compounding model of value creation. More teams, sites, and use cases have converged onto a single platform — transforming Science Exchange from an optional tool into the default mechanism for engaging external R&D across the organization.

**A growth curve, not a single moment**  
Completed orders processed through Science Exchange, year by year:

**2022**  
**86** completed orders  
**2023**  
**172** completed orders  
**2024**  
**296** completed orders  
**2025**  
**505** completed orders

Annual external R&D spend grew in parallel — from approximately $5.5M in 2022 to nearly $19M in 2025, with cumulative spend now exceeding $100M.

**Scale at a glance**  
- **$100M+** in cumulative external R&D spend orchestrated through the platform since 2015  
- **1,500+** R&D engagements processed end-to-end  
- **295 unique suppliers** actively engaged under one master agreement  
- **445 active researchers and procurement users** across the company’s global footprint  
- **~6× growth** in annual order volume from 2022 to 2025

**Early proof of active savings**
The Savings Initiative is still in its first year, but it has already produced a meaningful proof point: a 10% supplier discount negotiated by the Science Exchange team — on a supplier the company had been unable to secure a discount with through years of direct negotiation. The outcome is now serving as a template for similar engagements with other enterprise customers.

## A Lasting Partnership

### Why This Model Sustains and Scales Over Time

The durability of this partnership reflects four design principles that align with how global R&D organizations actually operate.

- **Mirror the operating reality of a global enterprise.** Science Exchange was deployed site by site and team by team — matching the company’s distributed structure rather than forcing a one-size-fits-all rollout.
- **Integrate with the systems already in place.** The platform operates inside the company’s existing enterprise stack — SharePoint, ELN, Ariba, Power BI — so adoption did not require parallel infrastructure.
- **Evolve as customer priorities evolve.** Phase one focused on infrastructure. Phase two emerged as procurement leadership shifted from visibility to measurable cost discipline.
- **Align around measurable outcomes.** The Savings Initiative is structured with shared performance targets — meaning Science Exchange has a direct stake in delivering savings, not just maintaining platform availability.

## The Operating Layer Behind Modern R&D Execution

For this top-10 global biopharmaceutical company, Science Exchange has become more than a procurement platform. Over more than a decade, it has evolved into the operating layer through which external R&D is executed — connecting researchers, suppliers, and procurement in a single system that supports both scale and control.

The introduction of active savings marks the next phase. As R&D investment continues to rise, organizations are no longer looking solely for visibility into external spend — they are looking for mechanisms that directly shape outcomes.
